June 2025 — DNB General Medicine

Discuss the aetiopathogenesis and treatment of chronic hepatitis C infection. [5+5]

Write about pathobiology of obesity. Discuss its management. [5+5]

What are the different types of ventricular arrhythmias? Discuss their clinical features and management. [2+(3+5)]

Ambulatory blood pressure monitoring.

Renovascular hypertension.

Discuss testosterone transport and metabolism. How do you approach a case of gynaecomastia? [5+5]

Define obstructive sleep apnea (OSA)/hypopnea syndrome.

What are the risk factors for OSA?

How will you diagnose it and assess its severity?

Discuss its treatment.

What are myelodysplastic syndromes?

Write the classification of these syndromes.

Discuss complications following hematopoietic cell transplantation.

What are the causes of hypophosphatemia? Discuss clinical manifestations and treatment of severe hypophosphatemia. [3+(4+3)]

Write classification of diabetes mellitus. How will you manage hyperosmolar hyperglycemic state? [5+5]

Physiology of swallowing.

How do you approach a case of dysphagia?

Discuss the clinical features, diagnosis, differential diagnosis and treatment of myasthenia gravis.

How will you approach a case of dysponea?

Discuss the etiopathogenesis, differential diagnosis and management of lung abscess.

How will you differentiate between non-inflammatory and inflammatory arthritis?

ACR/EULAR classification criteria for diagnosis of systemic sclerosis.

Clinical features and management of scleroderma renal crisis.

What are the causes of dilated cardiomyopathy?

Discuss the diagnosis and management of dilated cardiomyopathy.

What are hepatic porphyrias.

Discuss the clinical features, diagnosis and treatment of acute intermittent porphyrias.

How do you approach a case of urethritis in men? Discuss its management in men.

Define orthostatic hypotension.

Enlist various causes of orthostatic hypotension.

Write about various clinical bedside tests for autonomic neuropathy.

Classify common interstitial lung diseases (ILDs).

Discuss the clinical features, diagnosis and management of idiopathic pulmonary fibrosis.

Enumerate non-infectious causes of chronic meningitis.

What are the signs and symptoms of chronic meningitis?

Discuss the clinical features and management of migraine.

Write down the differences between ulcerative colitis and Crohn's disease.

Enumerate extra intestinal manifestations of ulcerative colitis.

How will you treat a case of ulcerative colitis?

Nontuberculous mycobacterial infections.

What is BpaLM regime in the management of tuberculosis?

What are the cardiovascular abnormalities associated with chronic kidney disease?

Briefly describe hemodialysis.

What are various tests for exocrine pancreatic functions?

Discuss the clinical features, diagnosis and treatment of chronic pancreatitis. [2+2+3]

What are chronic granulomatous diseases?

Write about monoclonal antibodies which are approved for clinical use in autoimmune diseases.

What are various autoimmune polyendocrine syndromes (APS)?

Discuss their clinical features and diagnosis.

Enumerate different vasculitis syndromes.

Discuss about Behcet syndrome.

Discuss the physiology and organisation of human sleep.

Define narcolepsy and write its treatment.

Enumerate various psychostimulant drugs.

Discuss clinical features of its overdose.

Treatment of acute and chronic overdose.

What are post traumatic stress disorders?

How will you diagnose them?

Discuss their treatment.

How do you manage refractory ascites?

Discuss hepatorenal syndrome.

What are the indications of liver transplantation?

Define metabolomics and write its clinical applications.

Discuss the aetiopathogenesis of chronic obstructive pulmonary diseases (COPD).

What are the recent advances in management of chronic obstructive pulmonary diseases?

What is neuromyelitis optica spectrum disorder? Discuss its diagnostic criteria, clinical features, and treatment.

What are paraneoplastic syndromes? Enlist antibodies associated with paraneoplastic syndromes of the nervous system. Write the treatment of humoral hypercalcemia of malignancy.

What is the P-SPIKES approach?

Enumerate the common symptoms of terminally ill patients.

Write about advance care planning in terminally ill patients for palliative management.

What are renal failure indices?

Write about peritoneal dialysis.

What is cardiac resynchronisation therapy?

Discuss the indication of ICD implantation in heart diseases.

Clinical features and diagnosis of thalassemia major.

Discuss about immune mediated adverse reactions of blood transfusion.

What are telomere spectrum disorders?

What are the methods to measure the length of telomeres?

Discuss the clinical features of dyskeratosis congenita.